A standardized treatment protocol for adult SARS in Hong Kong

From: So, et al. Lancet 2003;361:1615-6

(1)Antibacterial treatment

Start levofloxacin 500 mg once daily intravenously or orally

Or clarithromycin 500 mg twice daily orally plus amoxicillin and clavulanic acid 375 mg three times daily orally if patient <18 years, pregnant, or suspected to have tuberculosis

(2)Ribavirin and methylprednisolone

Add combination treatment with ribavirin and methylprednisolone when:

Extensive or bilateral chest radiographic involvement

Or persistent chest radiographic involvement and persistent high fever for 2 days

Or clinical, chest radiographic, or laboratory findings suggestive of worsening

Or oxygen saturation <95% in room air